Estradiol

REF 21-07

The Estradiol kit is a solid phase immunoassay intended for the quantitative determination of estradiol in human serum and plasma.

Estradiol is a sex hormone with a molecular weight of 272,4 Da. Estradiol is the strongest natural estrogen and is produced mainly by the ovaries and the placenta. Smaller amounts of estradiol are also produced by the adrenal cortex, and in men in the testes.

The measurement of estradiol in plasma provides insight into ovarian functions. The monitoring of estradiol levels is important in evaluating amenorrhea, the onset of menopause, fetal-placental competence during early stages of pregnancy and infertility in women. Monitoring estradiol levels is essential during ovarian hyperstimulation for in vitro fertilization (IVF), because oocyte recovery time depends on follicular development, which in turn depends on the level of estradiol.

The clinical intended use is:
• to support the diagnosis of infertility in women,
• monitoring of ovarian stimulation,
• to support the diagnosis of peri-menopause (in women) and
• to support the follow-up of normal pregnancy during early stages.