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Gonadotropin FSH

REF 21-06

ELISA kit ("sandwich" type) for the quantitativedeterminationof follicle-stimulating hormonein human serum.

Follicle-stimulating hormone (FSH) is a glycoprotein with molecular weight ca.30 000 Da consisting of two subunits, alpha and beta. FSH is secreted by frontal lobe of pituitary gland.

Together with LH and testosterone, FSH is vitally important for spermatogenesis in spermatic ducts of testicles. In pubescent females FSH induces follicle growth and maturation in ovaries. Increased FSH levels are observed in patients with different forms of hypogonadism (primary ovary or testicle insufficiency, polycystic ovaries, menopause etc), renal insufficiency, cirrhosis or aftereffect of castration. As a rule, decreased FSH levels are observed in case of testicle malignancies.

FSH measurement is useful for diagnosis of menopause, exact determination of ovulation time and for endocrine therapy monitoring.

Kit volume, wells (including controls) 96
Analytical sensitivity, mlU/mL 0.25
Precision: Intra Assay Variation, % < 8
Range of evaluated concentrations, mlU/mL 0.25100
Incubation time, minutes 60
Incubation temperature, 37
Shelf life, month 12