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Gonadotropin LH

REF 21-05

ELISA kit ("sandwich" type) for the quantitative determination of luteinizing hormone in human serum.

Luteinizing hormone (LH) is a glycoprotein with  molecular weight ca.  30 000 Da consisting of two subunits, α and β. LH is secreted by the frontal lobe of pituitary gland and stimulates testosterone synthesis in testicles. Together with the other hormones, LH regulates menstrual cycle in females.

Increased LH levels are observed in patients with different forms of hypogonadism (primary ovarian or testicle insufficiency, polycystic ovary, menopause etc), renal insufficiency and cirrhosis. Decreased LH levels that can result in sterility in both sexes, are observed at dysfunctions of hypothalamus or frontal lobe of pituitary gland
LH measurement is useful for diagnosing menopause, exact ovulation  time definition  and for endocrine therapy monitoring.

Kit volume, wells (including controls) 96
Analytical sensitivity, mlU/ml 0,25
Precision: Intra Assay Variation, % < 8
Range of evaluated concentrations, mlU/ml 0–100
Incubation time, minutes 60
Incubation temperature, °Ñ 37
Shelf life, month 12