REF 24-06
ELISA kit for the quantitative determination of autoantibodies against thyroid peroxidase in human serum.
Autoantibodies against thyroid peroxidase (Anti-TPO) autoantibodies are mainly IgG and, less frequently, IgM. TPO is a key enzyme in the biosynthesis of thyroid hormones. In healthy individuals, concentrations of Anti-TPO in serum may reach 30 U/ml. Quantity exceeding this limit is the sign of an autoimmune process that usually leads to thyroid dysfunction, mainly due to reduced thyroxin secretion. Serum anti-TPO antibodies assay is used for diagnostics of autoimmune thyroid diseases, such as idiopatic mixoedema, Hashimoto thyroiditis and Graves disease.
| Kit volume, wells (including controls) |
96 |
| Analytical sensitivity, U/ml |
4 |
| Precision: Intra Assay Variation, % |
< 8 |
| Range of evaluated concentrations, U/ml |
0–500 |
| Incubation time, minutes |
30+30 |
| Incubation temperature, °Ñ |
37 |
| Shelf life, month |
12 |
