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17-OH progesterone ELISA kit

REF 20-03

The 17-OH-Progesterone ELISA kit is intended for quantitativedeterminationof 17-OH progesteronein human serum and human plasma.

17-OH-progesterone (17-OHP) is a steroid hormone produced by suprarenal gland cortex and sex glands. The measurement of 17 OHP in serum can be used to monitor the activity of 21-hydroxylase of the suprarenal gland cortex. Deficiencies in 21-hydroxylase that are most commonly found in congenital adrenal hyperplasia result in excessive secretion of 17-OHP. However, deficiencies in 11-hydroxylase lead to moderately increase of the 17-OHP level. Therefore, the analysis of 17-OHP plays a significant role in the differential diagnostics of congenital hyperplasia of suprarenal gland cortex.

In addition, levels of 17-OHP are influenced by circadian rhythm and correlate with the adrenal secretion of cortisol. Maximal levels are found in samples collected in the morning.

Kit volume, wells (including controls) 96
Analitical sensitivity, nmol/L 0.3
Range of evaluated concentrations, nmol/L 0.3-60
Incubations 30 min + 10 min at 37C

or

30 min at 37C + 15-30 min at RT

Shelf life, months 12

MSDS 17-OH-Progesterone kit